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Targeting MicroRNAs in Cancer: Rationale, Strategies and Challenges
MicroRNAs (miRNAs) are evolutionary conserved small non-coding RNAs that regulate gene expression. Early studies have shown that miRNA expression is deregulated in cancer, and experimental data indicate that cancer phenotypes can be modified by targeting miRNA expression. Based on these observations...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3904431/ https://ncbi.nlm.nih.gov/pubmed/20885409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd3179 |
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