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Targeting MDMX for Cancer Therapy: Rationale, Strategies, and Challenges
The oncogene MDMX, also known as MDM4 is a critical negative regulator of the tumor suppressor p53 and has been implicated in the initiation and progression of human cancers. Increasing evidence indicates that MDMX is often amplified and highly expressed in human cancers, promotes cancer cell growth...
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| 出版年: | Front Oncol |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7419686/ https://ncbi.nlm.nih.gov/pubmed/32850448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.01389 |
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