Epithelial-mesenchymal transition sensitizes breast cancer cells to cell death via the fungus-derived sesterterpenoid ophiobolin A

The epithelial–mesenchymal transition (EMT) imparts properties of cancer stem-like cells, including resistance to frequently used chemotherapies, necessitating the identification of molecules that induce cell death specifically in stem-like cells with EMT properties. Herein, we demonstrate that brea...

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Pubblicato in:Sci Rep
Autori principali: Reisenauer, Keighley N., Tao, Yongfeng, Das, Provas, Song, Shuxuan, Svatek, Haleigh, Patel, Saawan D., Mikhail, Sheridan, Ingros, Alec, Sheesley, Peter, Masi, Marco, Boari, Angela, Evidente, Antonio, Kornienko, Alexander, Romo, Daniel, Taube, Joseph
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8137940/
https://ncbi.nlm.nih.gov/pubmed/34017048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89923-9
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