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Total Synthesis and Anticancer Activity of (+)-Hypercalin C and Congeners
The hypercalins are dearomatized acylphloroglucinols with a pendant complex cyclopentane ring that exhibit activity against several cancer cell lines. We report the first total synthesis of (+)-hypercalin C employing a convergent strategy that enabled dissection of the essential structural features...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6438696/ https://ncbi.nlm.nih.gov/pubmed/30600887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201812909 |
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