Epithelial-mesenchymal transition sensitizes breast cancer cells to cell death via the fungus-derived sesterterpenoid ophiobolin A

The epithelial–mesenchymal transition (EMT) imparts properties of cancer stem-like cells, including resistance to frequently used chemotherapies, necessitating the identification of molecules that induce cell death specifically in stem-like cells with EMT properties. Herein, we demonstrate that brea...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Reisenauer, Keighley N., Tao, Yongfeng, Das, Provas, Song, Shuxuan, Svatek, Haleigh, Patel, Saawan D., Mikhail, Sheridan, Ingros, Alec, Sheesley, Peter, Masi, Marco, Boari, Angela, Evidente, Antonio, Kornienko, Alexander, Romo, Daniel, Taube, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8137940/
https://ncbi.nlm.nih.gov/pubmed/34017048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89923-9
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