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Pan-cancer Drivers are Recurrent Transcriptional Regulatory Heterogeneities in Early-stage Luminal Breast Cancer

The heterogeneous composition of solid tumors is known to impact disease progression and response to therapy. Malignant cells coexist in different regulatory states that can be accessed transcriptomically by single-cell RNA sequencing, but these methods have many caveats related to sensitivity, nois...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Singh, Shambhavi, Sutcliffe, Matthew D., Repich, Kathy, Atkins, Kristen A., Harvey, Jennifer A., Janes, Kevin A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8137565/
https://ncbi.nlm.nih.gov/pubmed/33531373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-20-1034
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