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Pan-cancer Drivers are Recurrent Transcriptional Regulatory Heterogeneities in Early-stage Luminal Breast Cancer

The heterogeneous composition of solid tumors is known to impact disease progression and response to therapy. Malignant cells coexist in different regulatory states that can be accessed transcriptomically by single-cell RNA sequencing, but these methods have many caveats related to sensitivity, nois...

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Detalles Bibliográficos
Publicado en:Cancer Res
Main Authors: Singh, Shambhavi, Sutcliffe, Matthew D., Repich, Kathy, Atkins, Kristen A., Harvey, Jennifer A., Janes, Kevin A.
Formato: Artigo
Idioma:Inglês
Publicado: 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8137565/
https://ncbi.nlm.nih.gov/pubmed/33531373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-20-1034
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