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Pan-cancer Drivers are Recurrent Transcriptional Regulatory Heterogeneities in Early-stage Luminal Breast Cancer

The heterogeneous composition of solid tumors is known to impact disease progression and response to therapy. Malignant cells coexist in different regulatory states that can be accessed transcriptomically by single-cell RNA sequencing, but these methods have many caveats related to sensitivity, nois...

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Bibliografske podrobnosti
izdano v:Cancer Res
Main Authors: Singh, Shambhavi, Sutcliffe, Matthew D., Repich, Kathy, Atkins, Kristen A., Harvey, Jennifer A., Janes, Kevin A.
Format: Artigo
Jezik:Inglês
Izdano: 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8137565/
https://ncbi.nlm.nih.gov/pubmed/33531373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-20-1034
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