The human tRNA-guanine transglycosylase displays promiscuous nucleobase preference but strict tRNA specificity

Base-modification can occur throughout a transfer RNA molecule; however, elaboration is particularly prevalent at position 34 of the anticodon loop (the wobble position), where it functions to influence protein translation. Previously, we demonstrated that the queuosine modification at position 34 c...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Fergus, Claire, Al-qasem, Mashael, Cotter, Michelle, McDonnell, Ciara M, Sorrentino, Emiliano, Chevot, Franciane, Hokamp, Karsten, Senge, Mathias O, Southern, John M, Connon, Stephen J, Kelly, Vincent P
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2021
Soggetti:
Chemical Biology and Nucleic Acid Chemistry
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8136771/
https://ncbi.nlm.nih.gov/pubmed/34009357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab289
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