The human tRNA-guanine transglycosylase displays promiscuous nucleobase preference but strict tRNA specificity

Base-modification can occur throughout a transfer RNA molecule; however, elaboration is particularly prevalent at position 34 of the anticodon loop (the wobble position), where it functions to influence protein translation. Previously, we demonstrated that the queuosine modification at position 34 c...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Fergus, Claire, Al-qasem, Mashael, Cotter, Michelle, McDonnell, Ciara M, Sorrentino, Emiliano, Chevot, Franciane, Hokamp, Karsten, Senge, Mathias O, Southern, John M, Connon, Stephen J, Kelly, Vincent P
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2021
Onderwerpen:
Chemical Biology and Nucleic Acid Chemistry
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8136771/
https://ncbi.nlm.nih.gov/pubmed/34009357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab289
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