The human tRNA-guanine transglycosylase displays promiscuous nucleobase preference but strict tRNA specificity

Base-modification can occur throughout a transfer RNA molecule; however, elaboration is particularly prevalent at position 34 of the anticodon loop (the wobble position), where it functions to influence protein translation. Previously, we demonstrated that the queuosine modification at position 34 c...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Fergus, Claire, Al-qasem, Mashael, Cotter, Michelle, McDonnell, Ciara M, Sorrentino, Emiliano, Chevot, Franciane, Hokamp, Karsten, Senge, Mathias O, Southern, John M, Connon, Stephen J, Kelly, Vincent P
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Chemical Biology and Nucleic Acid Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8136771/
https://ncbi.nlm.nih.gov/pubmed/34009357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab289
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