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Insights into substrate promiscuity of human seryl-tRNA synthetase

Seryl-tRNA synthetase (SerRS) attaches L-serine to the cognate serine tRNA (tRNA(Ser)) and the noncognate selenocysteine tRNA (tRNA(Sec)). The latter activity initiates the anabolic cycle of selenocysteine (Sec), proper decoding of an in-frame Sec UGA codon, and synthesis of selenoproteins across al...

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Detalles Bibliográficos
Publicado en:RNA
Main Authors: Holman, Kaitlyn M., Puppala, Anupama K., Lee, Jonathan W., Lee, Hyun, Simonović, Miljan
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5648036/
https://ncbi.nlm.nih.gov/pubmed/28808125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.061069.117
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