The Mechanism of Pre-transfer Editing in Yeast Mitochondrial Threonyl-tRNA Synthetase

Accurate translation of mRNA into protein is a fundamental biological process critical for maintaining normal cellular functions. To ensure translational fidelity, aminoacyl-tRNA synthetases (aaRSs) employ pre-transfer and post-transfer editing activities to hydrolyze misactivated and mischarged ami...

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Autors principals: Ling, Jiqiang, Peterson, Kaitlyn M., Simonović, Ivana, Söll, Dieter, Simonović, Miljan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Protein Synthesis and Degradation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436575/
https://ncbi.nlm.nih.gov/pubmed/22773845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.372920
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