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The tRNA A76 Hydroxyl Groups Control Partitioning of the tRNA-dependent Pre- and Post-transfer Editing Pathways in Class I tRNA Synthetase

Aminoacyl-tRNA synthetases catalyze ATP-dependent covalent coupling of cognate amino acids and tRNAs for ribosomal protein synthesis. Escherichia coli isoleucyl-tRNA synthetase (IleRS) exploits both the tRNA-dependent pre- and post-transfer editing pathways to minimize errors in translation. However...

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Publicat a:J Biol Chem
Autors principals: Cvetesic, Nevena, Bilus, Mirna, Gruic-Sovulj, Ita
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447971/
https://ncbi.nlm.nih.gov/pubmed/25873392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.648568
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