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Aminoacyl Transfer Rate Dictates Choice of Editing Pathway in Threonyl-tRNA Synthetase

Aminoacyl-tRNA synthetases hydrolyze aminoacyl adenylates and aminoacyl-tRNAs formed from near-cognate amino acids, thereby increasing translational fidelity. The contributions of pre- and post-transfer editing pathways to the fidelity of Escherichia coli threonyl-tRNA synthetase (ThrRS) were invest...

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Detalhes bibliográficos
Main Authors: Minajigi, Anand, Francklyn, Christopher S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911285/
https://ncbi.nlm.nih.gov/pubmed/20504770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.105320
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