Nalaganje...
Post-Golgi carriers, not lysosomes, confer lysosomal properties to pre-degradative organelles in normal and dystrophic axons
Lysosomal trafficking and maturation in neurons remain poorly understood and are unstudied in vivo despite high disease relevance. We generated neuron-specific transgenic mice to track vesicular CTSD acquisition, acidification, and traffic within the autophagic-lysosomal pathway in vivo, revealing t...
Shranjeno v:
| izdano v: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2021
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8135226/ https://ncbi.nlm.nih.gov/pubmed/33910020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.109034 |
| Oznake: |
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