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Lysosome trafficking and signaling in health and neurodegenerative diseases

Lysosomes, single-membrane organelles defined by a uniquely strong acidic lumenal pH and high content of acid hydrolases, are the shared degradative compartments of the endocytic and autophagic pathways. These pathways, and especially lysosomes, are points of particular vulnerability in many neurode...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Neurobiol Dis
Main Authors: Lie, Pearl P.Y., Nixon, Ralph A.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6381838/
https://ncbi.nlm.nih.gov/pubmed/29859318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2018.05.015
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