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Lysosome trafficking and signaling in health and neurodegenerative diseases

Lysosomes, single-membrane organelles defined by a uniquely strong acidic lumenal pH and high content of acid hydrolases, are the shared degradative compartments of the endocytic and autophagic pathways. These pathways, and especially lysosomes, are points of particular vulnerability in many neurode...

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Bibliografiska uppgifter
I publikationen:Neurobiol Dis
Huvudupphovsmän: Lie, Pearl P.Y., Nixon, Ralph A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6381838/
https://ncbi.nlm.nih.gov/pubmed/29859318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2018.05.015
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