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The aging lysosome: an essential catalyst for late-onset neurodegenerative diseases

Lysosomes figure prominently in theories of aging as the proteolytic system most responsible for eliminating growing burdens of damaged proteins and organelles in aging neurons and other long lived cells. Newer evidence shows that diverse experimental measures known to extend lifespan in invertebrat...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta Proteins Proteom
Autor principal: Nixon, Ralph A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7388076/
https://ncbi.nlm.nih.gov/pubmed/32416272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2020.140443
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