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The aging lysosome: an essential catalyst for late-onset neurodegenerative diseases

Lysosomes figure prominently in theories of aging as the proteolytic system most responsible for eliminating growing burdens of damaged proteins and organelles in aging neurons and other long lived cells. Newer evidence shows that diverse experimental measures known to extend lifespan in invertebrat...

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Bibliographische Detailangaben
Veröffentlicht in:Biochim Biophys Acta Proteins Proteom
1. Verfasser: Nixon, Ralph A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7388076/
https://ncbi.nlm.nih.gov/pubmed/32416272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2020.140443
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