Llwytho...

Histone deacetylase 7 mediates endothelin-1-induced connective tissue growth factor expression in human lung fibroblasts through p300 and activator protein-1 activation

BACKGROUND: Histone deacetylase (HDAC) inhibition was reported to ameliorate lung fibrosis in animal models. However, little is known about the underlying mechanism of HDAC7 in the regulation of CTGF production in lung fibroblasts. METHODS: The role of HDAC7 in CTGF production caused by ET-1 stimula...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biomed Sci
Prif Awduron: Hua, Hung-Sheng, Wen, Heng-Ching, Weng, Chih-Ming, Lee, Hong-Sheng, Chen, Bing-Chang, Lin, Chien-Huang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8135160/
https://ncbi.nlm.nih.gov/pubmed/34011384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-021-00735-5
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