Bioenergetic and inflammatory systemic phenotypes in Alzheimer’s disease APOE ε4‐carriers

We examined the impact of an APOE ε4 genotype on Alzheimer's disease (AD) subject platelet and lymphocyte metabolism. Mean platelet mitochondrial cytochrome oxidase Vmax activity was lower in APOE ε4 carriers and lymphocyte Annexin V, a marker of apoptosis, was significantly higher. Proteins th...

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Библиографические подробности
Опубликовано в: :Aging Cell
Главные авторы: Wilkins, Heather M., Wang, Xiaowan, Menta, Blaise W., Koppel, Scott J., Bothwell, Rebecca, Becker, Annette M., Anderson, Heidi, Schwartz, Erin, Pei, Dong, Yellapu, Nanda K., Chalise, Prabhakar, Gouvion, Cynthia M., Haeri, Mohammad, Burns, Jeffrey M., Swerdlow, Russell H.
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2021
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Original Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8135087/
https://ncbi.nlm.nih.gov/pubmed/33939248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13356
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