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Bioenergetic and inflammatory systemic phenotypes in Alzheimer’s disease APOE ε4‐carriers
We examined the impact of an APOE ε4 genotype on Alzheimer's disease (AD) subject platelet and lymphocyte metabolism. Mean platelet mitochondrial cytochrome oxidase Vmax activity was lower in APOE ε4 carriers and lymphocyte Annexin V, a marker of apoptosis, was significantly higher. Proteins th...
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| Publicado no: | Aging Cell |
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| Principais autores: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8135087/ https://ncbi.nlm.nih.gov/pubmed/33939248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13356 |
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