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Unique evolutionary trajectories of breast cancers with distinct genomic and spatial heterogeneity

Breast cancers exhibit intratumoral heterogeneity associated with disease progression and therapeutic resistance. To define the sources and the extent of heterogeneity, we performed an in-depth analysis of the genomic architecture of three chemoradiation-naïve breast cancers with well-defined clinic...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Phung, Tanya N., Webster, Timothy H., Lenkiewicz, Elizabeth, Malasi, Smriti, Andreozzi, Mariacarla, McCullough, Ann E., Anderson, Karen S., Pockaj, Barbara A., Wilson, Melissa A., Barrett, Michael T.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8134446/
https://ncbi.nlm.nih.gov/pubmed/34011996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-90170-1
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