The association of genomic lesions and PD-1/PD-L1 expression in resected triple-negative breast cancers

BACKGROUND: Elevated PD-L1 expression on tumor cells, a context associated with an adaptive immune response, has been linked to the total burden of copy number variants (CNVs) in aneuploid tumors, to microsatellite instability (MSI), and to specific genomic driver lesions, including loss of PTEN, MY...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res
Main Authors: Barrett, Michael T., Lenkiewicz, Elizabeth, Malasi, Smriti, Basu, Anamika, Yearley, Jennifer Holmes, Annamalai, Lakshmanan, McCullough, Ann E., Kosiorek, Heidi E., Narang, Pooja, Wilson Sayres, Melissa A., Chen, Meixuan, Anderson, Karen S., Pockaj, Barbara A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042255/
https://ncbi.nlm.nih.gov/pubmed/29996881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-018-1004-0
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