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Photocatalytic carbanion generation from C–H bonds – reductant free Barbier/Grignard-type reactions

We report a redox-neutral method for the generation of carbanions from benzylic C–H bonds in a photocatalytic Grignard-type reaction. The combination of photo- and hydrogen atom transfer (HAT) catalysis enables the abstraction of a benzylic hydrogen atom, generating a radical intermediate. This radi...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Chem Sci
Prif Awduron: Berger, Anna Lucia, Donabauer, Karsten, König, Burkhard
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Royal Society of Chemistry 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8133029/
https://ncbi.nlm.nih.gov/pubmed/34040714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc04987h
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