A BAFF/APRIL axis regulates obesogenic diet-driven weight gain

The impact of immune mediators on weight homeostasis remains underdefined. Interrogation of resistance to diet-induced obesity in mice lacking a negative regulator of Toll-like receptor signaling serendipitously uncovered a role for B cell activating factor (BAFF). Here we show that overexpression o...

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Publicado no:Nat Commun
Main Authors: Chan, Calvin C., Harley, Isaac T. W., Pfluger, Paul T., Trompette, Aurelien, Stankiewicz, Traci E., Allen, Jessica L., Moreno-Fernandez, Maria E., Damen, Michelle S. M. A., Oates, Jarren R., Alarcon, Pablo C., Doll, Jessica R., Flick, Matthew J., Flick, Leah M., Sanchez-Gurmaches, Joan, Mukherjee, Rajib, Karns, Rebekah, Helmrath, Michael, Inge, Thomas H., Weisberg, Stuart P., Pamp, Sünje J., Relman, David A., Seeley, Randy J., Tschöp, Matthias H., Karp, Christopher L., Divanovic, Senad
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8131685/
https://ncbi.nlm.nih.gov/pubmed/34006859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23084-1
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