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Type I interferon sensing unlocks dormant adipocyte inflammatory potential

White adipose tissue inflammation, in part via myeloid cell contribution, is central to obesity pathogenesis. Mechanisms regulating adipocyte inflammatory potential and consequent impact of such inflammation in disease pathogenesis remain poorly defined. We show that activation of the type I interfe...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Chan, Calvin C., Damen, Michelle S. M. A., Moreno-Fernandez, Maria E., Stankiewicz, Traci E., Cappelletti, Monica, Alarcon, Pablo C., Oates, Jarren R., Doll, Jessica R., Mukherjee, Rajib, Chen, Xiaoting, Karns, Rebekah, Weirauch, Matthew T., Helmrath, Michael A., Inge, Thomas H., Divanovic, Senad
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7265526/
https://ncbi.nlm.nih.gov/pubmed/32488081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16571-4
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