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Identification of Compounds Protective Against G93A SOD1 Toxicity for the Treatment of Amyotrophic Lateral Sclerosis
OBJECTIVE: The underlying cause of amyotrophic lateral sclerosis (ALS), a progressive neurodegenerative disorder, remains unknown. However, there is strong evidence that one pathophysiological mechanism, toxic protein misfolding and/or aggregation, may trigger motor neuron dysfunction and loss. Sinc...
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| Udgivet i: | Amyotroph Lateral Scler |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8131116/ https://ncbi.nlm.nih.gov/pubmed/21073276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/17482968.2010.522586 |
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