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The role of sex, age and genetic polymorphisms of CYP enzymes on the pharmacokinetics of anticholinergic drugs

There is evidence that use of drugs with anticholinergic properties increases the risk of cognitive impairment, and increased exposure to these drugs potentiates this risk. Anticholinergic drugs are commonly used even with associated risk of adverse events. Aging, sex, and genetic polymorphisms of c...

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Publicat a:Pharmacol Res Perspect
Autors principals: Trenaman, Shanna C., Bowles, Susan K., Andrew, Melissa K., Goralski, Kerry
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8130657/
https://ncbi.nlm.nih.gov/pubmed/34003603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.775
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