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The role of sex, age and genetic polymorphisms of CYP enzymes on the pharmacokinetics of anticholinergic drugs

There is evidence that use of drugs with anticholinergic properties increases the risk of cognitive impairment, and increased exposure to these drugs potentiates this risk. Anticholinergic drugs are commonly used even with associated risk of adverse events. Aging, sex, and genetic polymorphisms of c...

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Publicado en:Pharmacol Res Perspect
Autores principales: Trenaman, Shanna C., Bowles, Susan K., Andrew, Melissa K., Goralski, Kerry
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8130657/
https://ncbi.nlm.nih.gov/pubmed/34003603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.775
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