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Discovery of novel JAK2 and EGFR inhibitors from a series of thiazole-based chalcone derivatives

The Janus kinase (JAK) and epidermal growth factor receptor (EGFR) have been considered as potential targets for cancer therapy due to their role in regulating proliferation and survival of cancer cells. In the present study, the aromatic alkyl-amino analogs of thiazole-based chalcone were selected...

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Publicat a:RSC Med Chem
Autors principals: Sanachai, Kamonpan, Aiebchun, Thitinan, Mahalapbutr, Panupong, Seetaha, Supaphorn, Tabtimmai, Lueacha, Maitarad, Phornphimon, Xenikakis, Iakovos, Geronikaki, Athina, Choowongkomon, Kiattawee, Rungrotmongkol, Thanyada
Format: Artigo
Idioma:Inglês
Publicat: RSC 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8130606/
https://ncbi.nlm.nih.gov/pubmed/34046625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0md00436g
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