Biological Evaluation and Molecular Dynamics Simulation of Chalcone Derivatives as Epidermal Growth Factor-Tyrosine Kinase Inhibitors

Targeted cancer therapy has become a high potential cancer treatment. Epidermal growth factor receptor (EGFR), which plays an important role in cell signaling, enhanced cell survival and proliferation, has been suggested as molecular target for the development of novel cancer therapeutics. In this s...

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Detalles Bibliográficos
Publicado en:Molecules
Autores principales: Sangpheak, Kanyani, Tabtimmai, Lueacha, Seetaha, Supaphorn, Rungnim, Chompoonut, Chavasiri, Warinthorn, Wolschann, Peter, Choowongkomon, Kiattawee, Rungrotmongkol, Thanyada
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6471738/
https://ncbi.nlm.nih.gov/pubmed/30897725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24061092
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