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Identification of Vinyl Sulfone Derivatives as EGFR Tyrosine Kinase Inhibitor: In Vitro and In Silico Studies

Epidermal growth factor receptor (EGFR), overexpressed in many types of cancer, has been proved as a high potential target for targeted cancer therapy due to its role in regulating proliferation and survival of cancer cells. In the present study, a series of designed vinyl sulfone derivatives was sc...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Aiebchun, Thitinan, Mahalapbutr, Panupong, Auepattanapong, Atima, Khaikate, Onnicha, Seetaha, Supaphorn, Tabtimmai, Lueacha, Kuhakarn, Chutima, Choowongkomon, Kiattawee, Rungrotmongkol, Thanyada
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8069501/
https://ncbi.nlm.nih.gov/pubmed/33921332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26082211
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