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Insights into the Binding Recognition and Susceptibility of Tofacitinib toward Janus Kinases
[Image: see text] Janus kinases (JAKs) are enzymes involved in signaling pathways that affect hematopoiesis and immune cell functions. JAK1, JAK2, and JAK3 play different roles in numerous diseases of the immune system and have also been considered as potential targets for cancer therapy. In the pre...
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| Publicado en: | ACS Omega |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Chemical Society
2020
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6964278/ https://ncbi.nlm.nih.gov/pubmed/31956784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b02800 |
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