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Rab40–Cullin5 complex regulates EPLIN and actin cytoskeleton dynamics during cell migration
Rab40b is a SOCS box–containing protein that regulates the secretion of MMPs to facilitate extracellular matrix remodeling during cell migration. Here, we show that Rab40b interacts with Cullin5 via the Rab40b SOCS domain. We demonstrate that loss of Rab40b–Cullin5 binding decreases cell motility an...
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| Veröffentlicht in: | J Cell Biol |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Rockefeller University Press
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8129794/ https://ncbi.nlm.nih.gov/pubmed/33999101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202008060 |
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