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The role and regulation of Rab40b–Tks5 complex during invadopodia formation and cancer cell invasion

Invadopodia formation and extracellular matrix degradation are key events during cancer cell invasion, yet little is known about mechanisms mediating these processes. Here, we report that Rab40b plays a key role in mediating invadopodia function during breast cancer cell invasion. We also identify T...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Jacob, Abitha, Linklater, Erik, Bayless, Brian A., Lyons, Traci, Prekeris, Rytis
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201011/
https://ncbi.nlm.nih.gov/pubmed/27789576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.193904
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