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NBR1 is a critical step in the repression of thermogenesis of p62-deficient adipocytes through PPARγ
Activation of non-shivering thermogenesis is considered a promising approach to lower body weight in obesity. p62 deficiency in adipocytes reduces systemic energy expenditure but its role in sustaining mitochondrial function and thermogenesis remains unresolved. NBR1 shares a remarkable structural s...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8129077/ https://ncbi.nlm.nih.gov/pubmed/34001883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23085-0 |
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