NBR1 is a critical step in the repression of thermogenesis of p62-deficient adipocytes through PPARγ

Activation of non-shivering thermogenesis is considered a promising approach to lower body weight in obesity. p62 deficiency in adipocytes reduces systemic energy expenditure but its role in sustaining mitochondrial function and thermogenesis remains unresolved. NBR1 shares a remarkable structural s...

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Vydáno v:Nat Commun
Hlavní autoři: Huang, Jianfeng, Linares, Juan F., Duran, Angeles, Xia, Wenmin, Saltiel, Alan R., Müller, Timo D., Diaz-Meco, Maria T., Moscat, Jorge
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8129077/
https://ncbi.nlm.nih.gov/pubmed/34001883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23085-0
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