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Adipocyte p62/SQSTM1 suppresses tumorigenesis through opposite regulations of metabolism in adipose tissue and tumor
Obesity is a leading risk factor for cancer. However, understanding the cross-talk between adipocytes and tumor cells in vivo, independently of dietary contributions, is a major gap in the field. Here we used a prostate cancer (PCa) mouse model in which the signaling adaptor p62/Sqstm1 is selectivel...
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| 發表在: | Cancer Cell |
|---|---|
| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5896786/ https://ncbi.nlm.nih.gov/pubmed/29634950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2018.03.001 |
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