p62/SQSTM1 by binding to vitamin D receptor inhibits hepatic stellate cell activity, fibrosis and liver cancer

Hepatic stellate cells (HSC) play critical roles in liver fibrosis and hepatocellular carcinoma (HCC). Vitamin D receptor (VDR) activation in HSC inhibits liver inflammation and fibrosis. We found that p62/SQSTM1, a protein upregulated in liver parenchymal cells but downregulated in HCC-associated H...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Cancer Cell
Autores principales: Duran, Angeles, Hernandez, Eloy D., Reina-Campos, Miguel, Castilla, Elias A., Subramaniam, Shankar, Raghunandan, Sindhu, Roberts, Lewis R., Kisseleva, Tatiana, Karin, Michael, Diaz-Meco, Maria T., Moscat, Jorge
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081228/
https://ncbi.nlm.nih.gov/pubmed/27728806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2016.09.004
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares