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Rational Design of Peptide-Based Inhibitors Disrupting Protein-Protein Interactions
Protein-protein interactions (PPIs) are well-established as a class of promising drug targets for their implications in a wide range of biological processes. However, drug development toward PPIs is inevitably hampered by their flat and wide interfaces, which generally lack suitable pockets for liga...
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| Pubblicato in: | Front Chem |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8128998/ https://ncbi.nlm.nih.gov/pubmed/34017824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2021.682675 |
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