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Peptide-based inhibitors of protein–protein interactions: biophysical, structural and cellular consequences of introducing a constraint
Protein–protein interactions (PPIs) are implicated in the majority of cellular processes by enabling and regulating the function of individual proteins. Thus, PPIs represent high-value, but challenging targets for therapeutic intervention. The development of constrained peptides represents an emergi...
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| Publicado no: | Chem Sci |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society of Chemistry
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8098664/ https://ncbi.nlm.nih.gov/pubmed/33995995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d1sc00165e |
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