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Identification of selective protein–protein interaction inhibitors using efficient in silico peptide-directed ligand design
The development of protein–protein interaction (PPI) inhibitors with therapeutic value is of increasing importance as the first clinical agent has now been approved, but PPIs remain difficult targets for the development of small molecule ligands. This article describes a highly efficient approach to...
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| Publicado en: | Chem Sci |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Royal Society of Chemistry
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6482886/ https://ncbi.nlm.nih.gov/pubmed/31057779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc00059c |
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