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Computationally Designed Peptide Inhibitors of Protein-Protein Interactions in Membranes
We recently reported a computational method (CHAMP) to design sequence-specific peptides that bind to the membrane-embedded portions of transmembrane proteins. We successfully applied this method to design membrane-spanning peptides targeting the transmembrane domains of the α(IIb)-subunit of integr...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2719017/ https://ncbi.nlm.nih.gov/pubmed/18642886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800687h |
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