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Computationally Designed Peptide Inhibitors of Protein-Protein Interactions in Membranes

We recently reported a computational method (CHAMP) to design sequence-specific peptides that bind to the membrane-embedded portions of transmembrane proteins. We successfully applied this method to design membrane-spanning peptides targeting the transmembrane domains of the α(IIb)-subunit of integr...

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Sonraí Bibleagrafaíochta
Main Authors: Caputo, Gregory A., Litvinov, Rustem I., Li, Wei, Bennett, Joel S., DeGrado, William F., Yin, Hang
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719017/
https://ncbi.nlm.nih.gov/pubmed/18642886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800687h
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