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Mutational analyses of novel rat models with targeted modifications in inflammatory bowel disease susceptibility genes

Mutations and single base pair polymorphisms in various genes have been associated with increased susceptibility to inflammatory bowel disease (IBD). We have created a series of rat strains carrying targeted genetic alterations within three IBD susceptibility genes: Nod2, Atg16l1, and Il23r, using C...

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Bibliografiske detaljer
Udgivet i:Mamm Genome
Main Authors: Men, Hongsheng, Hankins, Miriam A., Bock, Anagha S., Beaton, Benjamin P., Davis, Daniel J., Chesney, Kari L., Bryda, Elizabeth C.
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8128796/
https://ncbi.nlm.nih.gov/pubmed/33843019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-021-09868-2
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