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The Atg16l1 gene: characterization of wild type, knock-in, and knock-out phenotypes in rats

ATG16L1 is a ubiquitous autophagy gene responsible, in part, for formation of the double-membrane bound autophagosome that delivers unwanted cellular debris and intracellular pathogens to the lysosome for degradation. A single, nonsynonymous adenine to guanine polymorphism resulting in a threonine t...

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Bibliographic Details
Published in:Physiol Genomics
Main Authors: Chesney, Kari L., Men, Hongsheng, Hankins, Miriam A., Bryda, Elizabeth C.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8285577/
https://ncbi.nlm.nih.gov/pubmed/33818130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00114.2020
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