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The phenotypes of ATG9, ATG16 and ATG9/16 knock-out mutants imply autophagy-dependent and -independent functions

Macroautophagy is a highly conserved intracellular bulk degradation system of all eukaryotic cells. It is governed by a large number of autophagy proteins (ATGs) and is crucial for many cellular processes. Here, we describe the phenotypes of Dictyostelium discoideum ATG16(−) and ATG9(−)/16(−) cells...

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Publicat a:Open Biol
Autors principals: Xiong, Qiuhong, Ünal, Can, Matthias, Jan, Steinert, Michael, Eichinger, Ludwig
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422124/
https://ncbi.nlm.nih.gov/pubmed/25878144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.150008
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