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Derivation of a Germline Competent Transgenic Fischer 344 Embryonic Stem Cell Line

Embryonic stem (ES) cell-based gene manipulation is an effective method for the generation of mutant animal models in mice and rats. Availability of germline-competent ES cell lines from inbred rat strains would allow for creation of new genetically modified models in the desired genetic background....

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Détails bibliographiques
Auteurs principaux: Men, Hongsheng, Bryda, Elizabeth C.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577902/
https://ncbi.nlm.nih.gov/pubmed/23437152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056518
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