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Derivation of a Germline Competent Transgenic Fischer 344 Embryonic Stem Cell Line
Embryonic stem (ES) cell-based gene manipulation is an effective method for the generation of mutant animal models in mice and rats. Availability of germline-competent ES cell lines from inbred rat strains would allow for creation of new genetically modified models in the desired genetic background....
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3577902/ https://ncbi.nlm.nih.gov/pubmed/23437152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056518 |
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