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A new interaction between BRCA2 and DDX5 promotes the repair of DNA breaks at transcribed chromatin

In a recent report, we have revealed a new interaction between the BRCA2 DNA repair associated protein (BRCA2) and the DEAD-box helicase 5 (DDX5) at DNA breaks that promotes unwinding DNA-RNA hybrids within transcribed chromatin and favors repair. Interestingly, BRCA2–DDX5 interaction is impaired in...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Gómez-González, Belen, Sessa, Gaetana, Carreira, Aura, Aguilera, Andrés
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8128217/
https://ncbi.nlm.nih.gov/pubmed/34027046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2021.1910474
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