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Exposure time versus cytotoxicity for anticancer agents
PURPOSE: Time is a critical factor in drug action. The duration of inhibition of the target or residence time of the drug molecule on the target often guides drug scheduling. METHODS: The effects of time on the concentration-dependent cytotoxicity of approved and investigational agents [300 compound...
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| Publicat a: | Cancer Chemother Pharmacol |
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| Autors principals: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8127868/ https://ncbi.nlm.nih.gov/pubmed/31102023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-019-03863-w |
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