Epigenome-wide DNA methylation analysis of small cell lung cancer cell lines suggests potential chemotherapy targets

BACKGROUND: Small cell lung cancer (SCLC) is an aggressive neuroendocrine lung cancer. SCLC progression and treatment resistance involve epigenetic processes. However, links between SCLC DNA methylation and drug response remain unclear. We performed an epigenome-wide study of 66 human SCLC cell line...

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Dettagli Bibliografici
Pubblicato in:Clin Epigenetics
Autori principali: Krushkal, Julia, Silvers, Thomas, Reinhold, William C., Sonkin, Dmitriy, Vural, Suleyman, Connelly, John, Varma, Sudhir, Meltzer, Paul S., Kunkel, Mark, Rapisarda, Annamaria, Evans, David, Pommier, Yves, Teicher, Beverly A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318526/
https://ncbi.nlm.nih.gov/pubmed/32586373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-00876-8
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