Epigenome-wide DNA methylation analysis of small cell lung cancer cell lines suggests potential chemotherapy targets

BACKGROUND: Small cell lung cancer (SCLC) is an aggressive neuroendocrine lung cancer. SCLC progression and treatment resistance involve epigenetic processes. However, links between SCLC DNA methylation and drug response remain unclear. We performed an epigenome-wide study of 66 human SCLC cell line...

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Publicado en:Clin Epigenetics
Main Authors: Krushkal, Julia, Silvers, Thomas, Reinhold, William C., Sonkin, Dmitriy, Vural, Suleyman, Connelly, John, Varma, Sudhir, Meltzer, Paul S., Kunkel, Mark, Rapisarda, Annamaria, Evans, David, Pommier, Yves, Teicher, Beverly A.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318526/
https://ncbi.nlm.nih.gov/pubmed/32586373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-00876-8
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