Sarcoma Cell Line Screen of Oncology Drugs and Investigational Agents Identifies Patterns Associated with Gene and microRNA Expression

The diversity in sarcoma phenotype and genotype make treatment of this family of diseases exceptionally challenging. Sixty-three human adult and pediatric sarcoma lines were screened with 100 FDA approved oncology agents and 345 investigational agents. The investigational agents library enabled comp...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Teicher, Beverly A., Polley, Eric, Kunkel, Mark, Evans, David, Silvers, Thomas, Delosh, Rene, Laudeman, Julie, Ogle, Chad, Reinhart, Russell, Selby, Michael, Connelly, John, Harris, Erik, Monks, Anne, Morris, Joel
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636476/
https://ncbi.nlm.nih.gov/pubmed/26351324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0074
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