Sarcoma Cell Line Screen of Oncology Drugs and Investigational Agents Identifies Patterns Associated with Gene and microRNA Expression

The diversity in sarcoma phenotype and genotype make treatment of this family of diseases exceptionally challenging. Sixty-three human adult and pediatric sarcoma lines were screened with 100 FDA approved oncology agents and 345 investigational agents. The investigational agents library enabled comp...

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Udgivet i:Mol Cancer Ther
Main Authors: Teicher, Beverly A., Polley, Eric, Kunkel, Mark, Evans, David, Silvers, Thomas, Delosh, Rene, Laudeman, Julie, Ogle, Chad, Reinhart, Russell, Selby, Michael, Connelly, John, Harris, Erik, Monks, Anne, Morris, Joel
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636476/
https://ncbi.nlm.nih.gov/pubmed/26351324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0074
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