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Tau forms oligomeric complexes on microtubules that are distinct from tau aggregates
Tau is a microtubule-associated protein, which promotes neuronal microtubule assembly and stability. Accumulation of tau into insoluble aggregates known as neurofibrillary tangles (NFTs) is a pathological hallmark of several neurodegenerative diseases. The current hypothesis is that small, soluble o...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8126857/ https://ncbi.nlm.nih.gov/pubmed/33952699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2021461118 |
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