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Detyrosinated microtubules spatially constrain lysosomes facilitating lysosome–autophagosome fusion

Microtubule post-translational modifications impart functional diversity to microtubules by affecting their dynamics, organization, and interaction with proteins. Using super-resolution microscopy, we show that only a small subpopulation of microtubules are detyrosinated in epithelial cells, while a...

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Bibliografski detalji
Izdano u:J Cell Biol
Glavni autori: Mohan, Nitin, Sorokina, Elena M., Verdeny, Ione Vilanova, Alvarez, Angel Sandoval, Lakadamyali, Melike
Format: Artigo
Jezik:Inglês
Izdano: Rockefeller University Press 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6363446/
https://ncbi.nlm.nih.gov/pubmed/30567713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201807124
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